Chicory extrct
Chicory Extract
CAS: 68650-43-1
Molecular Formula:
Chicory extrct - Names and Identifiers
Chicory extrct - Physico-chemical Properties
| Use | Use chicory extract has obvious control effect on blood uric acid and blood lipid levels of quail suffering from hyperuricemia and hypertriglyceridemia, indicating that chicory has obvious lipid-lowering and uric acid-lowering effects. Natural products extracted from chicory are widely used as green feed additives, natural food ingredients, drug carriers and vaccine adjuvants. |
Chicory extrct - Experimental study on the establishment of quail hyperuricemia model and the effect of chicory extract on it
from hownet
Author:
Liu Xiaoqing , Zhang Bing , Hu Jinhong , Liu Chunmei , Hong Qingtao , Zhang , holes
Abstract:
objective: to shape hyperuricemia animal model similar to human metabolism and observe the effect of chicory extract on it. Methods: The quail was selected as a model animal, and the yeast bait was used as a modeling agent to shape the hyperuricemia model, and the serum uric acid and other biochemical indexes of quail were dynamically detected, to observe the effect of chicory extract on the serum uric acid level of the model animal. Results: the serum uric acid level of quails fed with yeast (15g/kg) for 7 days significantly increased for 5 weeks. A small dose of chicory extract administered for 7 days can significantly reduce the yeast-induced blood uric acid rise in quails and fight against the transient increase in blood sugar, and the effect of administration for 14 days is better than that of the positive control drug benzbromarone. Conclusion:(1) the model is an ideal animal model for screening traditional Chinese medicine for prevention and treatment of hyperuricemia and studying its mechanism. (2) chicory extract has obvious effect of lowering uric acid. (3) the mechanism of modeling and the mechanism of drug action need to be further studied.
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Key words:
quail hyperuricemia yeast chicory extract
DOI:
10.7661/CJIM.2003.1.44
cited:
year:
2003
Last Update：2024-01-02 23:10:35
Chicory extrct - Study on antioxidant activity of extracts KJ-I from cultivated chicory
Author:
Abstract:
objective to cultivate chicory (Cichorium endivia L.) it is a kind of chicory of Asteraceae, which has been proved to have certain antioxidant activity, but its application and antioxidant components are rarely studied. In this study, the antioxidant activity of cultivated chicory was systematically studied. Methods to extract and separate the cultivated chicory, screen the antioxidant active parts, and further study the antioxidant effect of the effective parts in vitro and in vivo. In addition, the preliminary safety evaluation was carried out, and the chemical components of the effective parts were isolated and identified, and the antioxidant activity was detected. Results The antioxidant activity of 60% ethanol eluate (KJ-I) in the extraction and separation process of cultivated chicory was significantly better than that of other extracts by FCR,ORAC and DPPH methods. In addition, KJ-I can effectively prevent the hemolysis of rabbit red blood cells induced by AAPH, suggesting that it can protect the body from oxidative stress injury. Protected by KJ-I tert-butyl hydroperoxide (t-BHP), hydrogen peroxide (H_2O_2) and 2,2 & prime;-azobis (2-methylpropylimidazole) dihydrochloride (AAPH) the experimental results of HepG2 cells, which caused oxidative damage and effectively reduced the level of reactive oxygen species (ROS) in damaged HepG2 cells, demonstrated that KJ-I had a protective effect on liver at the cellular level. In the experiment of acute liver injury induced by t-BHP in mice, Pathological observation showed that KJ-I can prevent the necrosis of liver tissue in damaged mice, while KJ-I can effectively reduce the levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum of damaged mice, reduces lipid peroxidation in liver tissue, increases reduced glutathione (GSH) levels in liver tissue, and increases superoxide dismutase (SOD) and glutathione-S-transferase (GST) in liver tissue activity, the above results further illustrate that KJ-I has the function of liver protection in in vivo experiments. Acute toxicity test and Salmonella typhimurium reverse mutation (Ames) test showed that KJ-I was safe and nontoxic. KJ-I was further isolated and the structures of the obtained compounds were identified. The antioxidant activities of these components were compared by ORAC and DPPH · scavenging ability test. KJ-I known ingredients include: kaempferol, kaempferol-3-o-β-d-glucoside, phenylethyl glucoside, adenosine, and the new compound 2-furfuryl alcohol-(5 & prime;& rarr;11)-1, 3-cyclopentadienyl [5,4-c]-1H-misoline. Among them, kaempferol has the strongest antioxidant activity, which may be the main component of the antioxidant activity of cultivated chicory. And 2-furfuryl alcohol-(5 & prime;& rarr;11)-1, 3-cyclopentaproz [5,4-c]-1H-misoline is a relatively rare derivative of the natural plant. Conclusion The extract KJ-I of chicory has a good antioxidant effect, and the most effective antioxidant component may be kaempferol. At the same time, KJ-I has a good liver protective effect. In addition, preliminary toxicity tests suggested that KJ-I was safe and nontoxic. Therefore, KJ-I may have potential development value in Food antioxidants and liver protective agents.
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Key words:
cultivated chicory Antioxidant liver protection misoline derivatives
meeting name:
Chinese conference on biological effects of reactive oxygen species
meeting place:
Xi'an, Shaanxi, China
cited:
Last Update：2023-08-16 22:09:50
Chicory extrct - Mask containing chicory extract and production method thereof
from Baidu Library
patent type:
invention patent
Application (patent) number:
CN201911036689.2
application date:
20191029
Public/Announcement Number:
CN110638706A
Public/announcement date:
20200103
applicant (patent):
Liaoning Zhongju Biotechnology Co., Ltd.
inventor:
National and provincial code:
CN210323
Abstract:
The invention discloses a mask containing chicory extract and a production method thereof. It belongs to the technical field of skin care products. Including the following parts by weight of components: purified water 70100 parts, glycerin 15 parts, erythritol 0.52 parts, carbomer 0.10.15 parts, sodium hyaluronate 0.050.1 parts, chicory extract 210 parts, Centella asiatica extract 0.050.1 parts, polygonum cuspidatum extract 0.050.1 parts, scutellaria root extract 0.050.1 parts, tea extract 0.050.1 parts, Glycyrrhiza glabra extract 0.050.1 parts, chrysanthemum extract 0.050.1 parts, rosemary leaf extract 0.050.1 parts, not only quality and safety, the effect of sustained mild, but also in the moisturizing at the same time, improve the symptoms of problematic skin.
Last Update：2023-08-16 22:09:50
Chicory extrct - Reference Information
| overview | chicory is a herbaceous plant with homology of perennial medicine and food in Asteraceae family, and has strong medicinal value. Xinjiang Chinese herbal medicine says chicory: "clearing heat, diuresis, diuresis, choleretic and anti-inflammatory." |
| use | chicory extract has obvious control effect on blood uric acid and blood lipid levels of quails suffering from hyperuricemia and hypertriglyceridemia, indicating that chicory has obvious lipid-lowering and uric acid-lowering effects. Natural products extracted from chicory are widely used as feed green additives, natural food ingredients, drug carriers and vaccine adjuvants. |
| production method | the dried chicory (Cichorium intybus L) fleshy rhizome is baked and crushed, and then extracted with water or light alcohol containing 20% ~ 40%. |
| EPA chemical information | information provided by: ofmpub.epa.gov (external link) |
Last Update：2024-04-09 21:11:58
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CAS: 68650-43-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
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Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
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